del(10q23) for Breast, Prostate
CIDEGEN
Delivery time
<1 week
Sample
Biopsy tissue
166,98€
PTEN deletion is observed in a variety of hematologic and solid tumors, including breast and prostate cancer. Loss of PTEN leads to dysregulated activation of the PI5-6 week/AKT/mTOR pathway, promoting cell proliferation and resistance to apoptosis. PTEN loss in HER2+ breast cancer does not respond to anti-HER2 therapies.