BLADDER CANCER – Sanger sequencing of the KRAS gene
LabGenetics
Delivery time
3-4 weeks
Sample
Biopsy tissue
Genetic testing for bladder cancer using Sanger sequencing of the KRAS gene allows for the identification of somatic mutations associated with aberrant activation of the RAS/MAPK pathway, which is involved in cell proliferation and survival. KRAS alterations are linked to a subgroup of bladder tumors with distinct biological behavior and potential therapeutic implications. This analysis contributes to molecular diagnosis, prognostic stratification, and the development of personalized therapies.