PERRAULT SYNDROME: CLINICAL EXOME PANEL (Sec. & CNVs) – 5 genes
LabGenetics
Delivery time
3-4 weeks
Sample
Blood
The Perrault Syndrome panel is designed to diagnose a condition characterized by congenital sensorineural hearing loss in both sexes and premature ovarian failure in women. The genetic alterations affect genes related to mitochondrial function and protein translation, resulting in a complex neurosensory and endocrine phenotype. Its detection allows for confirmation of the clinical diagnosis, optimization of reproductive follow-up, and appropriate family counseling. Genes analyzed: CLPP, HARS2, HSD17B4, LARS2, TWNK.